Pathogenes, a company in Florida specializing in treatments and diagnostic tools for EPM, is sponsoring a study of Oroquin-10, a new treatment for EPM. It’s not a double-blind study, however the company, Pathogenes, has a protocol they are asking owners to follow. Here are the links I sent my vet for the clinical trial for Oroquin-10. It has both treatment and preventive dosing options.
According to the EPM Horse web site, the Oroquin-10 trial
This field drug trial opened in May 2011. An in-vitro efficacy study has been completed for EPM, and a safety trial in horses. It is a ten-day dose of oral paste medication. An antibody test is required before and after the medication. Your vet has to fill out and submit the forms. A prescription will be sent to your veterinarian. There is no cost to enter the trial, the antibody blood tests total $78 (plus 2-day shipping) and the drug is about $150. As of August, 2011, 150 horses have been treated with no adverse effects. 94% are significantly better – more than one grade on the Mayhew scale.”
Additional information on the Oroquin-10 treatment:
- Drug info and study
- Drug trial description
- Peptide ELISA submission form
- Info on drug and webinar for study
The vet at Pathogenes was happy to talk to my vet about how Oroquin-10 can be used in a mare like Isis who has insulin resistance. The study meds are compounded at Franck’s Pharmacy. While I’m upset that Isis has EPM (again!), this study will offer a good opportunity to try a shorter treatment — and give my vet experience with the meds. Maybe this will help other horses who have EPM.